| Gene name: | ADRB2(ADRB2R;B2AR); |
| Protein name: | Beta-2 adrenergic receptor; |
| Alternative: | Beta-2 adrenoreceptor(Beta-2 adrenoceptor); |
| Organism: | Human (Homo sapiens). |
| Sub Unit: | Binds SLC9A3R1 and GPRASP1. Interacts with ARRB1 and ARRB2. Interacts with SRC, USP20 and USP33. |
| Function: | Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. The beta-2-adrenergic receptor binds epinephrine with an approximately 30-fold greater affinity than it does norepinephrine. |
| Subcellular Location: | Cell membrane Multi-pass membrane protein |
| Sequence length: | 413 |
| Sequence: | |
| 50: | MGQPGNGSAF | LLAPNGSHAP | DHDVTQERDE | VWVVGMGIVM | SLIVLAIVFG | |
| 100: | NVLVITAIAK | FERLQTVTNY | FITSLACADL | VMGLAVVPFG | AAHILMKMWT | |
| 150: | FGNFWCEFWT | SIDVLCVTAS | IETLCVIAVD | RYFAITSPFK | YQSLLTKNKA | |
| 200: | RVIILMVWIV | SGLTSFLPIQ | MHWYRATHQE | AINCYANETC | CDFFTNQAYA | |
| 250: | IASSIVSFYV | PLVIMVFVYS | RVFQEAKRQL | QKIDKSEGRF | HVQNLSQVEQ | |
| 300: | DGRTGHGLRR | SSKFCLKEHK | ALKTLGIIMG | TFTLCWLPFF | IVNIVHVIQD | |
| 350: | NLIRKEVYIL | LNWIGYVNSG | FNPLIYCRSP | DFRIAFQELL | CLRRSSLKAY | |
| 400: | GNGYSSNGNT | GEQSGYHVEQ | EKENKLLCED | LPGTEDFVGH | QGTVPSDNID | |
| 413: | SQGRNCSTND | SLL |
| 3D Structure: | N/A |
| MIM: | 109690 |
| SMR: | P07550 |
| UniGene: | Hs.2551 |
| KEGG: | hsa:154 |
| String: | P07550 |
| Pfam: | PF00001 |
| Uniprot: | P07550 |