Gene name: | ADRB2; |
Protein name: | Beta-2 adrenergic receptor; |
Alternative: | Beta-2 adrenoreceptor(Beta-2 adrenoceptor); |
Organism: | Dog (Canis familiarisCanis lupus familiaris). |
Sub Unit: | Binds SLC9A3R1 and GPRASP1. Interacts with ARRB1 and ARRB2. Interacts with SRC, USP20 and USP33. |
Function: | Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. The beta-2-adrenergic receptor binds epinephrine with an approximately 30-fold greater affinity than it does norepinephrine. |
Subcellular Location: | Cell membrane Multi-pass membrane protein |
Sequence length: | 415 |
Sequence: | |
50: | MGQPANRSVF | LLAPNGSHAP | DQGDSQERSE | AWVVGMGIVM | SLIVLAIVFG | |
100: | NVLVITAIAR | FERLQTVTNY | FITSLACADL | VMGLAVVPFG | ASHILMKMWT | |
150: | FGNFWCEFWT | SIDVLCVTAS | IETLCVIAVD | RYFAITSPFK | YQSLLTKNKA | |
200: | RVVILMVWIV | SGLTSFLPIQ | MHWYRATHQE | AINCYAKETC | CDFFTNQAYA | |
250: | IASSIVSFYL | PLVVMVFVYS | RVFQVAQRQL | QKIDRSEGRF | HAQNLSQVEQ | |
300: | DGRSGHGHRR | SSKFCLKEHK | ALKTLGIIMG | TFTLCWLPFF | IVNIVHVIQD | |
350: | NLIPKEVYIL | LNWVGYVNSA | FNPLIYCRSP | DFRIAFQELL | CLRRSSLKAY | |
400: | GNGYSNNSNS | RSDYAGEHSG | CHLGQEKDSE | LLCEDPPGTE | DRQGTVPSDS | |
415: | VDSQGRNCST | NDSLL |
3D Structure: | N/A |
UniGene: | Cfa.3770 |
KEGG: | cfa:403910 |
SMR: | P54833 |
STRING: | 9615.ENSCAFP00000027094 |
Pfam: | PF00001 |
String: | P54833 |
Uniprot: | P54833 |