| Gene name: | Ffar1(Gpr40); |
| Protein name: | Free fatty acid receptor 1; |
| Alternative: | G-protein coupled receptor 40; |
| Organism: | Rat (Rattus norvegicus). |
| Sub Unit: | N/A |
| Function: | Receptor for medium and long chain saturated and unsaturated fatty acids. Binding of the ligand increase intracellular calcium concentration and amplify glucose-stimulated insulin secretion. The activity of this receptor is mediated by G proteins that activate phospholipase C. Seems to act through a G(q) and G(i)-mediated pathway. |
| Subcellular Location: | Cell membrane Multi-pass membrane protein |
| Sequence length: | 300 |
| Sequence: | |
| 50: | MDLPPQLSFA | LYVSAFALGF | PLNLLAIRGA | VSHAKLRLTP | SLVYTLHLAC | |
| 100: | SDLLLAITLP | LKAVEALASG | VWPLPLPFCP | VFALAHFAPL | YAGGGFLAAL | |
| 150: | SAGRYLGAAF | PFGYQAIRRP | CYSWGVCVAI | WALVLCHLGL | ALGLEAPRGW | |
| 200: | VDNTTSSLGI | NIPVNGSPVC | LEAWDPDSAR | PARLSFSILL | FFLPLVITAF | |
| 250: | CYVGCLRALV | HSGLSHKRKL | RAAWVAGGAL | LTLLLCLGPY | NASNVASFIN | |
| 300: | |
| 3D Structure: | N/A |
| String: | Q8K3T4 |
| UniGene: | Rn.86438 |
| KEGG: | rno:266607 |
| STRING: | 10116.ENSRNOP00000028533 |
| Pfam: | PF00001 |
| Uniprot: | Q8K3T4 |