| Gene name: | Ffar1(Gpr40); |
| Protein name: | Free fatty acid receptor 1; |
| Alternative: | G-protein coupled receptor 40; |
| Organism: | Mouse (Mus musculus). |
| Sub Unit: | N/A |
| Function: | Receptor for medium and long chain saturated and unsaturated fatty acids. Binding of the ligand increase intracellular calcium concentration and amplify glucose-stimulated insulin secretion. The activity of this receptor is mediated by G-proteins that activate phospholipase C. Seems to act through a G(q) and G(i)-mediated pathway. |
| Subcellular Location: | Cell membrane Multi-pass membrane protein |
| Sequence length: | 300 |
| Sequence: | |
| 50: | MDLPPQLSFA | LYVSAFALGF | PLNLLAIRGA | VSHAKLRLTP | SLVYTLHLGC | |
| 100: | SDLLLAITLP | LKAVEALASG | AWPLPLPFCP | VFALAHFAPL | YAGGGFLAAL | |
| 150: | SAGRYLGAAF | PFGYQAIRRP | RYSWGVCVAI | WALVLCHLGL | ALGLETSGSW | |
| 200: | LDNSTSSLGI | NIPVNGSPVC | LEAWDPDSAR | PARLSFSILL | FFLPLVITAF | |
| 250: | CYVGCLRALV | RSGLSHKRKL | RAAWVAGGAL | LTLLLCLGPY | NASNVASFIN | |
| 300: | |
| 3D Structure: | N/A |
| STRING: | 10090.ENSMUSP00000055564 |
| SMR: | Q76JU9 |
| String: | Q76JU9 |
| UniGene: | Mm.425422 |
| KEGG: | mmu:233081 |
| Pfam: | PF00001 |
| Uniprot: | Q76JU9 |