Gene name: | TNFRSF10C(UNQ321/PRO366;DCR1;LIT;TRAILR3;TRID); |
Protein name:Alternative: CD: | Tumor necrosis factor receptor superfamily member 10C; TRAIL receptor without an intracellular domain;TNF-related apoptosis-inducing ligand receptor 3(TRAIL receptor 3;TRAIL-R3);Lymphocyte inhibitor of TRAIL;Decoy receptor 1(DcR1);Antagonist decoy receptor for TRAIL/Apo-2L;Decoy TRAIL receptor without death domain; CD263; |
Organism: | Human (Homo sapiens). |
Sub Unit: | N/A |
Function: | Receptor for the cytotoxic ligand TRAIL. Lacks a cytoplasmic death domain and hence is not capable of inducing apoptosis. May protect cells against TRAIL mediated apoptosis by competing with TRAIL-R1 and R2 for binding to the ligand. |
Subcellular Location: | Cell membrane Lipid-anchor GPI-anchor |
Sequence length: | 259 |
Sequence: | |
50: | MARIPKTLKF | VVVIVAVLLP | VLAYSATTAR | QEEVPQQTVA | PQQQRHSFKG | |
100: | EECPAGSHRS | EHTGACNPCT | EGVDYTNASN | NEPSCFPCTV | CKSDQKHKSS | |
150: | CTMTRDTVCQ | CKEGTFRNEN | SPEMCRKCSR | CPSGEVQVSN | CTSWDDIQCV | |
200: | EEFGANATVE | TPAAEETMNT | SPGTPAPAAE | ETMNTSPGTP | APAAEETMTT | |
250: | SPGTPAPAAE | ETMTTSPGTP | APAAEETMIT | SPGTPASSHY | LSCTIVGIIV | |
259: | LIVLLIVFV |
3D Structure: | N/A |
STRING: | 9606.ENSP00000310908 |
Pfam: | PF00020 |
UniGene: | Hs.655801 |
KEGG: | hsa:8794 |
String: | O14798 |
SMR: | O14798 |
MIM: | 603613 |
Uniprot: | O14798 |