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ELISA Kit FOR Thyrotropin receptor

B9855p
Data Sheet

Description

Gene name:TSHR;
Protein name:Thyrotropin receptor;
Alternative: Thyroid-stimulating hormone receptor(TSH-R);
Organism:Pig (Sus scrofa).

General Annotation

Sub Unit:Interacts (via the PDZ-binding motif) with SCRIB; regulates TSHR trafficking and function.
Function:Receptor for thyrothropin. Plays a central role in controlling thyroid cell metabolism. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Also acts as a receptor for thyrostimulin (GPA2+GPB5).
Subcellular Location:Cell membrane Multi-pass membrane protein

Protein Attributes:

Sequence length:764
Sequence:
50:MSLTPLLQLA | LLLALPRSLR | GKGCPSPPCE | CHQEDDFRVT | CKDIHSIPPL | 
100:PPNTQTLKFI | ETHLKTIPSR | AFSNLPNISR | IYLSIDATLQ | QLESQSFYNL | 
150:SKMTHIEIRN | TRSLTYINPG | ALKDLPLLKF | LGIFNTGLRI | FPDLTKVYST | 
200:DVFFILEITD | NPYMTSIPAN | AFQGLCNETL | TLKLYNNGFT | SVQGHAFNGT | 
250:KLDAVYLNKN | KYLTVIDKDA | FGGVFSGPTL | LDVSYTSVTA | LPPKGLEHLK | 
300:ELIARNTWTL | KKLPLSLSFL | HLTRADLSYP | SHCCAFKNQK | KIRGILESLM | 
350:CNESSIRSLR | QRKSVNAVNG | PFYQEYEEDL | GDSSVGNKEN | SKFQDTHSNS | 
400:HYYVFFEEQE | DEIIGFGQEL | KNPQEETLQA | FDSHYDYTVC | GGSEDMVCTP | 
450:KSDEFNPCED | IMGYRFLRIV | VWFVSLLALL | GNVFVLVILL | TSHYKLTVPR | 
500:FLMCNLAFAD | FCMGMYLLLI | ASVDLYTQSE | YYNHAIDWQT | GPGCNTAGFF | 
550:TVFASELSVY | TLTVITLERW | YAITFAMRLD | RKIRLRHAYA | IMAGGWVCCF | 
600:LLALLPLVGI | SSYAKVSICL | PMDTETPLAL | AYIILVLLLN | IVAFTIVCSC | 
650:YVKIYITVRN | PQYNPGDKDT | KIAKRMAVLI | FTDFMCMAPI | SFYALSALMN | 
700:KPLITVTNSK | ILLVLFYPLN | SCANPFLYAI | FTKAFQRDVF | ILLSKFGFCK | 
750:RQAQAYRGQR | VSPKNSTGIQ | VQKVTQNMRQ | SLPNMQDDYE | LLENSHLTHK | 
764:KHDQISKEYK | QPVL
3D Structure:N/A

Related Databases

UniGene:Ssc.16367
Pfam:PF00001
KEGG:ssc:397560
Uniprot:Q8SPP9

References