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ELISA Kit FOR Thyrotropin receptor

B9855d
Data Sheet

Description

Gene name:TSHR;
Protein name:Thyrotropin receptor;
Alternative: Thyroid-stimulating hormone receptor(TSH-R);
Organism:Dog (Canis familiarisCanis lupus familiaris).

General Annotation

Sub Unit:Interacts (via the PDZ-binding motif) with SCRIB; regulates TSHR trafficking and function.
Function:Receptor for thyrothropin. Plays a central role in controlling thyroid cell metabolism. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Also acts as a receptor for thyrostimulin (GPA2+GPB5).
Subcellular Location:Cell membrane Multi-pass membrane protein

Protein Attributes:

Sequence length:764
Sequence:
50:MRPPPLLHLA | LLLALPRSLG | GKGCPSPPCE | CHQEDDFRVT | CKDIHRIPTL | 
100:PPSTQTLKFI | ETQLKTIPSR | AFSNLPNISR | IYLSIDATLQ | RLESHSFYNL | 
150:SKMTHIEIRN | TRSLTSIDPD | ALKELPLLKF | LGIFNTGLGV | FPDVTKVYST | 
200:DVFFILEITD | NPYMASIPAN | AFQGLCNETL | TLKLYNNGFT | SIQGHAFNGT | 
250:KLDAVYLNKN | KYLSAIDKDA | FGGVYSGPTL | LDVSYTSVTA | LPSKGLEHLK | 
300:ELIARNTWTL | KKLPLSLSFL | HLTRADLSYP | SHCCAFKNQK | KIRGILESLM | 
350:CNESSIRSLR | QRKSVNTLNG | PFDQEYEEYL | GDSHAGYKDN | SQFQDTDSNS | 
400:HYYVFFEEQE | DEILGFGQEL | KNPQEETLQA | FDSHYDYTVC | GGNEDMVCTP | 
450:KSDEFNPCED | IMGYKFLRIV | VWFVSLLALL | GNVFVLIVLL | TSHYKLTVPR | 
500:FLMCNLAFAD | FCMGMYLLLI | ASVDLYTHSE | YYNHAIDWQT | GPGCNTAGFF | 
550:TVFASELSVY | TLTVITLERW | YAITFAMRLD | RKIRLRHAYA | IMVGGWVCCF | 
600:LLALLPLVGI | SSYAKVSICL | PMDTETPLAL | AYIILVLLLN | IVAFIIVCSC | 
650:YVKIYITVRN | PQYNPGDKDT | KIAKRMAVLI | FTDFMCMAPI | SFYALSALMN | 
700:KPLITVTNSK | ILLVLFYPLN | SCANPFLYAI | FTKAFQRDVF | ILLSKFGICK | 
750:RQAQAYRGQR | VSPKNSAGIQ | IQKVTRDMRQ | SLPNMQDEYE | LLENSHLTPN | 
764:KQGQISKEYN | QTVL
3D Structure:N/A

Related Databases

KEGG:cfa:403968
UniGene:Cfa.3837
STRING:9615.ENSCAFP00000025489
Pfam:PF00001
String:P14763
Uniprot:P14763

References