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ELISA Kit FOR Thyrotropin receptor

B9855b
Data Sheet

Description

Gene name:TSHR;
Protein name:Thyrotropin receptor;
Alternative: Thyroid-stimulating hormone receptor(TSH-R);
Organism:Bovine (Bos taurus).

General Annotation

Sub Unit:Interacts (via the PDZ-binding motif) with SCRIB; regulates TSHR trafficking and function.
Function:Receptor for thyrothropin. Plays a central role in controlling thyroid cell metabolism. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Also acts as a receptor for thyrostimulin (GPA2+GPB5).
Subcellular Location:Cell membrane Multi-pass membrane protein

Protein Attributes:

Sequence length:763
Sequence:
50:MRPTPLLRLA | LFLVLPSSLG | GERCPSPPCE | CRQEDDFRVT | CKDIQSIPSL | 
100:PPSTQTLKFI | ETHLKTIPSR | AFSNLPNISR | IYLSIDATLQ | QLESHSFYNL | 
150:SKVTHIEIRN | TRSLTYIDSG | ALKELPLLKF | LGIFNTGLRV | FPDLTKIYST | 
200:DVFFILEITD | NPYMTSIPAN | AFQGLCNETL | TLKLYNNGFT | SIQGHAFNGT | 
250:KLDAVYLNKN | KYLTVIGQDA | FAGVYSGPTL | LDISYTSVTA | LPSKGLEHLK | 
300:ELIARNTWTL | RKLPLSLSFL | HLTRADLSYP | SHCCAFKNQK | KIRGILQSLM | 
350:CNESSIRGLR | QRKSASALNG | PFYQEYEDLG | DGSAGYKENS | KFQDTQSNSH | 
400:YYVFFEEQED | EIIGFGQQLK | NPQEETLQAF | DSHYDYTVCG | GSEDMVCTPK | 
450:SDEFNPCEDI | MGYKFLRIVV | WFVSLLALLG | NVFVLVILLT | SHYKLTVPRF | 
500:LMCNLAFADF | CMGLYLLLIA | SVDLYTQSEY | YNHAIDWQTG | PGCNTAGFFT | 
550:VFASELSVYT | LTVITLERWH | AITFAMRLDR | KIRLWHAYVI | MLGGWVCCFL | 
600:LALLPLVGIS | SYAKVSICLP | MDTETPLALA | YIILVLLLNI | IAFIIVCACY | 
650:VKIYITVRNP | HYNPGDKDTR | IAKRMAVLIF | TDFMCMAPIS | FYALSALMNK | 
700:PLITVTNSKI | LLVLFYPLNS | CANPFLYAIF | TKAFQRDVFM | LLSKFGICKR | 
750:QAQAYRGQRV | SPKNSTGIRV | QKVPPDVRQS | LPNVQDDYEL | LENSHLTPKQ | 
763:QDQTSKEYKR | TVL
3D Structure:N/A

Related Databases

String:Q27987
UniGene:Bt.34
KEGG:bta:281553
Pfam:PF00001
Uniprot:Q27987

References