| Gene name: | Cxcr1(Il8ra); |
| Protein name:Alternative: CD: | C-X-C chemokine receptor type 1(CXC-R1;CXCR-1); High affinity interleukin-8 receptor A(IL-8R A); CD181; |
| Organism: | Rat (Rattus norvegicus). |
| Sub Unit: | N/A |
| Function: | Receptor to interleukin-8, which is a powerful neutrophils chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activate a phosphatidylinositol-calcium second messenger system. |
| Subcellular Location: | Cell membrane Multi-pass membrane protein |
| Sequence length: | 349 |
| Sequence: | |
| 50: | MAEAEYFIWI | APEGDFEEEF | GNITRMLPTG | EYFSPCKRVP | MTNRQAVVVF | |
| 100: | YALVFLLSLL | GNSLVMLVIL | YRRRTRSVTD | VYVLNLAIAD | LLFSLTLPFL | |
| 150: | AVSKWKGWIF | GTPLCKMVSL | LKEVNFFSGI | LLLACISVDR | YLAIVHATRT | |
| 200: | LTRKRYLVKF | VCMGTWGLSL | VLSLPFAIFR | QAYKPYRSGT | VCYEVLGEAT | |
| 250: | ADLRITLRGL | SHIFGFLLPL | FIMLVCYGLT | LRTLFKAHMR | QKRRAMWVIF | |
| 300: | AVVLVFLLCC | LPYNLVLLSD | TLLGAHLIQD | TCERRNNIDQ | ALYITEILGF | |
| 349: | SHSCLNPVIY | AFVGQSFRHE | FLKILANLVH | KEVLTHHSAS | FRTSLTTIY |
| 3D Structure: | N/A |
| KEGG: | rno:54258 |
| UniGene: | Rn.138115 |
| Pfam: | PF00001 |
| Uniprot: | P70612 |