| Gene name: | BMPR1A(ACVRLK3;ALK3); |
| Protein name:Alternative: CD: | Bone morphogenetic protein receptor type-1A(BMP type-1A receptor;BMPR-1A); Activin receptor-like kinase 3(ALK-3);Serine/threonine-protein kinase receptor R5(SKR5); CD292; |
| Organism: | Human (Homo sapiens). |
| Sub Unit: | N/A |
| Function: | On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for BMP-2 and BMP-4. |
| Subcellular Location: | Membrane Single-pass type I membrane protein |
| Sequence length: | 532 |
| Sequence: | |
| 50: | MPQLYIYIRL | LGAYLFIISR | VQGQNLDSML | HGTGMKSDSD | QKKSENGVTL | |
| 100: | APEDTLPFLK | CYCSGHCPDD | AINNTCITNG | HCFAIIEEDD | QGETTLASGC | |
| 150: | MKYEGSDFQC | KDSPKAQLRR | TIECCRTNLC | NQYLQPTLPP | VVIGPFFDGS | |
| 200: | IRWLVLLISM | AVCIIAMIIF | SSCFCYKHYC | KSISSRRRYN | RDLEQDEAFI | |
| 250: | PVGESLKDLI | DQSQSSGSGS | GLPLLVQRTI | AKQIQMVRQV | GKGRYGEVWM | |
| 300: | GKWRGEKVAV | KVFFTTEEAS | WFRETEIYQT | VLMRHENILG | FIAADIKGTG | |
| 350: | SWTQLYLITD | YHENGSLYDF | LKCATLDTRA | LLKLAYSAAC | GLCHLHTEIY | |
| 400: | GTQGKPAIAH | RDLKSKNILI | KKNGSCCIAD | LGLAVKFNSD | TNEVDVPLNT | |
| 450: | RVGTKRYMAP | EVLDESLNKN | HFQPYIMADI | YSFGLIIWEM | ARRCITGGIV | |
| 500: | EEYQLPYYNM | VPSDPSYEDM | REVVCVKRLR | PIVSNRWNSD | ECLRAVLKLM | |
| 532: | SECWAHNPAS | RLTALRIKKT | LAKMVESQDV | KI |
| 3D Structure: | N/A |
| UniGene: | Hs.524477 |
| MIM: | 174900 |
| MIM: | 158350 |
| Pfam: | PF01064 |
| String: | P36894 |
| SMR: | P36894 |
| STRING: | 9606.ENSP00000224764 |
| KEGG: | hsa:657 |
| Uniprot: | P36894 |