Gene name: | Bmp4(Bmp-4;Dvr-4); |
Protein name: | Bone morphogenetic protein 4(BMP-4); |
Alternative: | Bone morphogenetic protein 2B(BMP-2B); |
Organism: | Rat (Rattus norvegicus). |
Sub Unit: | Homodimer; disulfide-linked. Interacts with SOSTDC1, GREM2, RGMA, RGMB and RGMC (By similarity). Part of a complex consisting of TWSG1 and CHRD. |
Function: | Induces cartilage and bone formation. Acts in concert with PTHLH/PTHRP to stimulate ductal outgrowth during embryonic mammary development and to inhibit hair follicle induction. |
Subcellular Location: | Secreted extracellular space extracellular matrix |
Sequence length: | 408 |
Sequence: | |
50: | MIPGNRMLMV | VLLCQVLLGG | ATDASLIPET | GKKKVAEIQG | HAGGRRSGQS | |
100: | HELLRDFEAT | LLQMFGLRRR | PQPSKSAVIP | DYMRDLYRLQ | SGEEEEEEQS | |
150: | QGTGLEYPER | PASRANTVRS | FHHEEHLENI | PGTSESSAFR | FFFNLSSIPE | |
200: | NEVISSAELR | LFREQVDQGP | DWEQGFHRIN | IYEVMKPPAE | MVPGHLITRL | |
250: | LDTRLVRHNV | TRWETFDVSP | AVLRWTREKQ | PNYGLAIEVT | HLHQTRTHQG | |
300: | QHVRISRSLP | QGSGNWAQLR | PLLVTFGHDG | RGHTLTRRRA | KRSPKHHPQR | |
350: | SRKKNKNCRR | HSLYVDFSDV | GWNDWIVAPP | GYQAFYCHGD | CPFPLADHLN | |
400: | STNHAIVQTL | VNSVNSSIPK | ACCVPTELSA | ISMLYLDEYD | KVVLKNYQEM | |
408: | VVEGCGCR |
3D Structure: | N/A |
UniGene: | Rn.10318 |
String: | Q06826 |
SMR: | Q06826 |
Pfam: | PF00019 |
Uniprot: | Q06826 |