Gene name: | Bmp4(Bmp-4;Dvr-4); |
Protein name: | Bone morphogenetic protein 4(BMP-4); |
Alternative: | Bone morphogenetic protein 2B(BMP-2B); |
Organism: | Mouse (Mus musculus). |
Sub Unit: | Homodimer; disulfide-linked (By similarity). Interacts with SOSTDC1, GREM2, RGMA, RGMB and RGMC. Part of a complex consisting of TWSG1 and CHRD. |
Function: | Induces cartilage and bone formation. Acts in concert with PTHLH/PTHRP to stimulate ductal outgrowth during embryonic mammary development and to inhibit hair follicle induction. |
Subcellular Location: | Secreted extracellular space extracellular matrix |
Sequence length: | 408 |
Sequence: | |
50: | MIPGNRMLMV | VLLCQVLLGG | ASHASLIPET | GKKKVAEIQG | HAGGRRSGQS | |
100: | HELLRDFEAT | LLQMFGLRRR | PQPSKSAVIP | DYMRDLYRLQ | SGEEEEEEQS | |
150: | QGTGLEYPER | PASRANTVRS | FHHEEHLENI | PGTSESSAFR | FLFNLSSIPE | |
200: | NEVISSAELR | LFREQVDQGP | DWEQGFHRIN | IYEVMKPPAE | MVPGHLITRL | |
250: | LDTRLVHHNV | TRWETFDVSP | AVLRWTREKQ | PNYGLAIEVT | HLHQTRTHQG | |
300: | QHVRISRSLP | QGSGDWAQLR | PLLVTFGHDG | RGHTLTRRRA | KRSPKHHPQR | |
350: | SRKKNKNCRR | HSLYVDFSDV | GWNDWIVAPP | GYQAFYCHGD | CPFPLADHLN | |
400: | STNHAIVQTL | VNSVNSSIPK | ACCVPTELSA | ISMLYLDEYD | KVVLKNYQEM | |
408: | VVEGCGCR |
3D Structure: | N/A |
SMR: | P21275 |
String: | P21275 |
Pfam: | PF00019 |
UniGene: | Mm.6813 |
KEGG: | mmu:12159 |
STRING: | 10090.ENSMUSP00000098242 |
Uniprot: | P21275 |