| Gene name: | BMP4(BMP2B;DVR4); |
| Protein name: | Bone morphogenetic protein 4(BMP-4); |
| Alternative: | Bone morphogenetic protein 2B(BMP-2B); |
| Organism: | Human (Homo sapiens). |
| Sub Unit: | Homodimer; disulfide-linked (By similarity). Interacts with GREM2 (By similarity) and SOSTDC1. Part of a complex consisting of TWSG1 and CHRD. |
| Function: | Induces cartilage and bone formation. Also act in mesoderm induction, tooth development, limb formation and fracture repair. Acts in concert with PTHLH/PTHRP to stimulate ductal outgrowth during embryonic mammary development and to inhibit hair follicle induction. |
| Subcellular Location: | Secreted extracellular space extracellular matrix |
| Sequence length: | 408 |
| Sequence: | |
| 50: | MIPGNRMLMV | VLLCQVLLGG | ASHASLIPET | GKKKVAEIQG | HAGGRRSGQS | |
| 100: | HELLRDFEAT | LLQMFGLRRR | PQPSKSAVIP | DYMRDLYRLQ | SGEEEEEQIH | |
| 150: | STGLEYPERP | ASRANTVRSF | HHEEHLENIP | GTSENSAFRF | LFNLSSIPEN | |
| 200: | EVISSAELRL | FREQVDQGPD | WERGFHRINI | YEVMKPPAEV | VPGHLITRLL | |
| 250: | DTRLVHHNVT | RWETFDVSPA | VLRWTREKQP | NYGLAIEVTH | LHQTRTHQGQ | |
| 300: | HVRISRSLPQ | GSGNWAQLRP | LLVTFGHDGR | GHALTRRRRA | KRSPKHHSQR | |
| 350: | ARKKNKNCRR | HSLYVDFSDV | GWNDWIVAPP | GYQAFYCHGD | CPFPLADHLN | |
| 400: | STNHAIVQTL | VNSVNSSIPK | ACCVPTELSA | ISMLYLDEYD | KVVLKNYQEM | |
| 408: | VVEGCGCR |
| 3D Structure: | N/A |
| UniGene: | Hs.68879 |
| MIM: | 112262 |
| KEGG: | hsa:652 |
| Pfam: | PF00019 |
| SMR: | P12644 |
| STRING: | 9606.ENSP00000245451 |
| String: | P12644 |
| Uniprot: | P12644 |