Gene name: | BDNF; |
Protein name: | Brain-derived neurotrophic factor(BDNF); |
Alternative: | |
Organism: | Dog (Canis familiarisCanis lupus familiaris). |
Sub Unit: | Monomers and homodimers. Binds to NTRK2/TRKB. |
Function: | During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. |
Subcellular Location: | Secreted |
Sequence length: | 247 |
Sequence: | |
50: | MTILFLTMVI | SYFGCMKAAP | MKEASVRGQG | SLAYPGVRTH | GTLESVSGPK | |
100: | AGSRGLTSLA | DTFEHVIEEL | LDEDQKVRPN | EENNKDADLY | TSRVMLSSQV | |
150: | PLEPPLLFLL | EEYKNYLDAA | NMSMRVRRHS | DPARRGELSV | CDSISEWVTA | |
200: | ADKKTAVDMS | GGTVTVLEKV | PVSKGQLKQY | FYETKCNPMG | YTKEGCRGID | |
247: | KRHWNSQCRT | TQSYVRALTM | DSKKRIGWRF | IRIDTSCVCT | LTIKRGR |
3D Structure: | N/A |
STRING: | 9615.ENSCAFP00000014984 |
SMR: | Q7YRB4 |
UniGene: | Cfa.170 |
String: | Q7YRB4 |
KEGG: | cfa:403461 |
Pfam: | PF00243 |
Uniprot: | Q7YRB4 |