Gene name: | Ctgf(Ccn2); |
Protein name: | Connective tissue growth factor; |
Alternative: | CCN family member 2;Connective tissue growth-related protein; |
Organism: | Rat (Rattus norvegicus). |
Sub Unit: | N/A |
Function: | Major connective tissue mitoattractant secreted by vascular endothelial cells. Promotes proliferation and differentiation of chondrocytes (By similarity). Mediates heparin-and divalent cation-dependent cell adhesion in many cell types including fibroblasts, myofibroblasts, endothelial and epithelial cells (By similarity). Enhances fibroblast growth factor-induced DNA synthesis. |
Subcellular Location: | Secreted extracellular space extracellular matrix |
Sequence length: | 347 |
Sequence: | |
50: | MLASVAGPVS | LALVLLLCTR | PATGQDCSAQ | CQCAAEAAPR | CPAGVSLVLD | |
100: | GCGCCRVCAK | QLGELCTERD | PCDPHKGLFC | DFGSPANRKI | GVCTAKDGAP | |
150: | CVFGGSVYRS | GESFQSSCKY | QCTCLDGAVG | CVPLCSMDVR | LPSPDCPFPR | |
200: | RVKLPGKCCE | EWVCDEPKDR | TVVGPALAAY | RLEDTFGPDP | TMMRANCLVQ | |
250: | TTEWSACSKT | CGMGISTRVT | NDNTFCRLEK | QSRLCMVRPC | EADLEENIKK | |
300: | GKKCIRTPKI | AKPVKFELSG | CTSVKTYRAK | FCGVCTDGRC | CTPHRTTTLP | |
347: | VEFKCPDGEI | MKKNMMFIKT | CACHYNCPGD | NDIFESLYYR | KMYGDMA |
3D Structure: | N/A |
String: | Q9R1E9 |
UniGene: | Rn.17145 |
KEGG: | rno:64032 |
Pfam: | PF00007 |
Uniprot: | Q9R1E9 |