Gene name: | CTGF(CCN2); |
Protein name: | Connective tissue growth factor; |
Alternative: | CCN family member 2; |
Organism: | Pig (Sus scrofa). |
Sub Unit: | Monomer. |
Function: | Major connective tissue mitoattractant secreted by vascular endothelial cells. Promotes proliferation and differentiation of chondrocytes (By similarity). Mediates heparin-and divalent cation-dependent cell adhesion in many cell types including fibroblasts, myofibroblasts, endothelial and epithelial cells (By similarity). Enhances fibroblast growth factor-induced DNA synthesis. |
Subcellular Location: | Secreted extracellular space extracellular matrix Secreted |
Sequence length: | 349 |
Sequence: | |
50: | MSATGLSPVR | CAFVLLLALC | SRPASGQDCS | GQCQCAAGKR | RACPAGVSLV | |
100: | LDGCGCCRLC | AKQLGELCTE | RDPCDPHKGL | FCDFGSPANR | KIGVCTAKDG | |
150: | APCVFGGTVY | RSGESFQSSC | KYQCTCLDGA | VGCVPLCSMD | VRLPSPDCPF | |
200: | PRRVKLPGKC | CEEWVCDEPK | DHTVVGPALA | AYRLEDTFGP | DPTMMRANCL | |
250: | VQTTEWSACS | KTCGMGISTR | VTNDNAFCRL | EKQSRLCMVR | PCEADLEENI | |
300: | KKGKKCIRTP | KISKPVKFEL | SGCTSVKTYR | AKFCGVCTDG | RCCTPHRTTT | |
349: | LPVEFKCPDG | EVMKKSMMFI | KTCACHYNCP | GDNDIFESLY | YRKMYGDMA |
3D Structure: | N/A |
String: | O19113 |
UniGene: | Ssc.70001 |
Pfam: | PF00007 |
Uniprot: | O19113 |