| Gene name: | CTGF(CCN2); |
| Protein name: | Connective tissue growth factor; |
| Alternative: | CCN family member 2; |
| Organism: | Bovine (Bos taurus). |
| Sub Unit: | Monomer. |
| Function: | Major connective tissue mitoattractant secreted by vascular endothelial cells. Promotes proliferation and differentiation of chondrocytes (By similarity). Mediates heparin-and divalent cation-dependent cell adhesion in many cell types including fibroblasts, myofibroblasts, endothelial and epithelial cells (By similarity). Enhances fibroblast growth factor-induced DNA synthesis. |
| Subcellular Location: | Secreted extracellular space extracellular matrix Secreted |
| Sequence length: | 349 |
| Sequence: | |
| 50: | MSATGLGPVR | CAFVLLLALC | SRPASSQDCS | APCQCPAGPA | PRCPAGVSLV | |
| 100: | LDGCGCCRVC | AKQLSELCTE | RDPCDPHKGL | FCDFGSPANR | KIGVCTAKDG | |
| 150: | APCVFGGTVY | QSGESFQSSC | KYQCTCLDGS | VGCVPLCSVD | VRLPSPDCPF | |
| 200: | PRRVKLPGKC | CEEWVCDEPK | EHTVVGPALA | AYRPEDTFGP | DPTMIRANCL | |
| 250: | VQTTEWSACS | KTCGMGISTR | VTNDNAFCRL | EKQSRLCMVR | PCEADLEENI | |
| 300: | KKGKKCIRTP | KISKPIKFEL | SGCTSMKTYR | AKFCGVCTDG | RCCTPHRTTT | |
| 349: | LPVEFKCPDG | EVMKKSMMFI | KTCACHYNCP | GDNDIFESLY | YRKMYGDMA |
| 3D Structure: | N/A |
| KEGG: | bta:281103 |
| String: | O18739 |
| UniGene: | Bt.5240 |
| Pfam: | PF00007 |
| Uniprot: | O18739 |