| Gene name: | AREG(SDGF); |
| Protein name: | Amphiregulin(AR); |
| Alternative: | Colorectum cell-derived growth factor(CRDGF); |
| Organism: | Human (Homo sapiens). |
| Sub Unit: | The immature precursor interacts with CNIH. |
| Function: | Bifunctional growth-modulating glycoprotein. Inhibits growth of several human carcinoma cells in culture and stimulates proliferation of human fibroblasts and certain other tumor cells. |
| Subcellular Location: | Membrane Single-pass membrane protein |
| Sequence length: | 252 |
| Sequence: | |
| 50: | MRAPLLPPAP | VVLSLLILGS | GHYAAGLDLN | DTYSGKREPF | SGDHSADGFE | |
| 100: | VTSRSEMSSG | SEISPVSEMP | SSSEPSSGAD | YDYSEEYDNE | PQIPGYIVDD | |
| 150: | SVRVEQVVKP | PQNKTESENT | SDKPKRKKKG | GKNGKNRRNR | KKKNPCNAEF | |
| 200: | QNFCIHGECK | YIEHLEAVTC | KCQQEYFGER | CGEKSMKTHS | MIDSSLSKIA | |
| 250: | LAAIAAFMSA | VILTAVAVIT | VQLRRQYVRK | YEGEAEERKK | LRQENGNVHA | |
| 252: | IA |
| 3D Structure: | N/A |
| UniGene: | Hs.270833 |
| MIM: | 104640 |
| SMR: | P15514 |
| STRING: | 9606.ENSP00000264487 |
| String: | P15514 |
| KEGG: | hsa:374 |
| Uniprot: | P15514 |