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ELISA Kit FOR Angiotensin-converting enzyme

B0004m
Data Sheet

Description

Gene name:Ace(Dcp1);
Protein name:Alternative: CD:Angiotensin-converting enzyme(ACE); Dipeptidyl carboxypeptidase I;Kininase II; CD143;
Organism:Mouse (Mus musculus).

General Annotation

Sub Unit:N/A
Function:Converts angiotensin I to angiotensin II by release of the terminal His-Leu, this results in an increase of the vasoconstrictor activity of angiotensin. Also able to inactivate bradykinin, a potent vasodilator. Has also a glycosidase activity which releases GPI-anchored proteins from the membrane by cleaving the mannose linkage in the GPI moiety. This GPIase activity seems to be crucial for the egg-binding ability of the sperm.
Subcellular Location:Cell membrane Single-pass type I membrane protein

Protein Attributes:

Sequence length:1312
Sequence:
50:MGAASGQRGR | WPLSPPLLML | SLLVLLLQPS | PAPALDPGLQ | PGNFSPDEAG | 
100:AQLFAESYNS | SAEVVMFQST | VASWAHDTNI | TEENARRQEE | AALVSQEFAE | 
150:VWGKKAKELY | ESIWQNFTDS | KLRRIIGSIR | TLGPANLPLA | QRQQYNSLLS | 
200:NMSRIYSTGK | VCFPNKTATC | WSLDPELTNI | LASSRSYAKL | LFAWEGWHDA | 
250:VGIPLKPLYQ | DFTAISNEAY | RQDDFSDTGA | FWRSWYESPS | FEESLEHIYH | 
300:QLEPLYLNLH | AYVRRALHRR | YGDKYVNLRG | PIPAHLLGDM | WAQSWENIYD | 
350:MVVPFPDKPN | LDVTSTMVQK | GWNATHMFRV | SEEFFTSLGL | SPMPPEFWAE | 
400:SMLEKPTDGR | EVVCHASAWD | FYNRKDFRIK | QCTRVTMEQL | ATVHHEMGHV | 
450:QYYLQYKDLH | VSLRRGANPG | FHEAIGDVLA | LSVSTPAHLH | KIGLLDHVTN | 
500:DIESDINYLL | KMALEKIAFL | PFGYLVDQWR | WGVFSGRTPP | SRYNFDWWYL | 
550:RTKYQGICPP | VARNETHFDA | GAKFHIPNVT | PYIRYFVSFV | LQFQFHQALC | 
600:KEAGHQGPLH | QCDIYQSAQA | GAKLKQVLQA | GCSRPWQEVL | KDLVGSDALD | 
650:AKALLEYFQP | VSQWLEEQNQ | RNGEVLGWPE | NQWRPPLPDN | YPEGIDLETD | 
700:EAKADRFVEE | YDRTAQVLLN | EYAEANWQYN | TNITIEGSKI | LLEKSTEVSN | 
750:HTLKYGTRAK | TFDVSNFQNS | SIKRIIKKLQ | NLDRAVLPPK | ELEEYNQILL | 
800:DMETTYSLSN | ICYTNGTCMP | LEPDLTNMMA | TSRKYEELLW | AWKSWRDKVG | 
850:RAILPFFPKY | VEFSNKIAKL | NGYTDAGDSW | RSLYESDNLE | QDLEKLYQEL | 
900:QPLYLNLHAY | VRRSLHRHYG | SEYINLDGPI | PAHLLGNMWA | QTWSNIYDLV | 
950:APFPSAPNID | ATEAMIKQGW | TPRRIFKEAD | NFFTSLGLLP | VPPEFWNKSM | 
1000:LEKPTDGREV | VCHPSAWDFY | NGKDFRIKQC | TSVNMEDLVI | AHHEMGHIQY | 
1050:FMQYKDLPVT | FREGANPGFH | EAIGDIMALS | VSTPKHLYSL | NLLSTEGSGY | 
1100:EYDINFLMKM | ALDKIAFIPF | SYLIDQWRWR | VFDGSITKEN | YNQEWWSLRL | 
1150:KYQGLCPPVP | RSQGDFDPGS | KFHVPANVPY | VRYFVSFIIQ | FQFHEALCRA | 
1200:AGHTGPLHKC | DIYQSKEAGK | LLADAMKLGY | SKPWPEAMKL | ITGQPNMSAS | 
1250:AMMNYFKPLT | EWLVTENRRH | GETLGWPEYN | WAPNTARAEG | STAESNRVNF | 
1300:LGLYLEPQQA | RVGQWVLLFL | GVALLVATVG | LAHRLYNIRN | HHSLRRPHRG | 
1312:PQFGSEVELR | HS
3D Structure:N/A

Related Databases

SMR:P09470
UniGene:Mm.754
String:P09470
KEGG:mmu:11421
Pfam:PF01401
Uniprot:P09470

References