ELISA Kit FOR Low-density lipoprotein receptor-related protein 2

B0001h

Description

Gene name:	LRP2;
Protein name:	Low-density lipoprotein receptor-related protein 2(LRP-2);
Alternative:	Glycoprotein 330(gp330);Megalin;
Organism:	Human (Homo sapiens).

General Annotation

Sub Unit:	Binds plasminogen, extracellular matrix components, plasminogen activator-plasminogen activator inhibitor type I complex, apolipoprotein E-enriched beta-VLDL, lipoprotein lipase, lactoferrin, CLU/clusterin and calcium. Forms a multimeric complex together with a receptor-associated protein (RAP). Binds to ankyrin-repeat family A protein 2 (ANKRA2). Interacts with LRP2BP.
Function:	Acts together with cubilin to mediate HDL endocytosis (By similarity). May participate in regulation of parathyroid-hormone and para-thyroid-hormone-related protein release.
Subcellular Location:	Membrane Single-pass type I membrane protein Membrane coated pit

Protein Attributes:

Sequence length:	4655
Sequence:
50:	MDRGPAAVAC \| TLLLALVACL \| APASGQECDS \| AHFRCGSGHC \| IPADWRCDGT \|
100:	KDCSDDADEI \| GCAVVTCQQG \| YFKCQSEGQC \| IPNSWVCDQD \| QDCDDGSDER \|
150:	QDCSQSTCSS \| HQITCSNGQC \| IPSEYRCDHV \| RDCPDGADEN \| DCQYPTCEQL \|
200:	TCDNGACYNT \| SQKCDWKVDC \| RDSSDEINCT \| EICLHNEFSC \| GNGECIPRAY \|
250:	VCDHDNDCQD \| GSDEHACNYP \| TCGGYQFTCP \| SGRCIYQNWV \| CDGEDDCKDN \|
300:	GDEDGCESGP \| HDVHKCSPRE \| WSCPESGRCI \| SIYKVCDGIL \| DCPGREDENN \|
350:	TSTGKYCSMT \| LCSALNCQYQ \| CHETPYGGAC \| FCPPGYIINH \| NDSRTCVEFD \|
400:	DCQIWGICDQ \| KCESRPGRHL \| CHCEEGYILE \| RGQYCKANDS \| FGEASIIFSN \|
450:	GRDLLIGDIH \| GRSFRILVES \| QNRGVAVGVA \| FHYHLQRVFW \| TDTVQNKVFS \|
500:	VDINGLNIQE \| VLNVSVETPE \| NLAVDWVNNK \| IYLVETKVNR \| IDMVNLDGSY \|
550:	RVTLITENLG \| HPRGIAVDPT \| VGYLFFSDWE \| SLSGEPKLER \| AFMDGSNRKD \|
600:	LVKTKLGWPA \| GVTLDMISKR \| VYWVDSRFDY \| IETVTYDGIQ \| RKTVVHGGSL \|
650:	IPHPFGVSLF \| EGQVFFTDWT \| KMAVLKANKF \| TETNPQVYYQ \| ASLRPYGVTV \|
700:	YHSLRQPYAT \| NPCKDNNGGC \| EQVCVLSHRT \| DNDGLGFRCK \| CTFGFQLDTD \|
750:	ERHCIAVQNF \| LIFSSQVAIR \| GIPFTLSTQE \| DVMVPVSGNP \| SFFVGIDFDA \|
800:	QDSTIFFSDM \| SKHMIFKQKI \| DGTGREILAA \| NRVENVESLA \| FDWISKNLYW \|
850:	TDSHYKSISV \| MRLADKTRRT \| VVQYLNNPRS \| VVVHPFAGYL \| FFTDWFRPAK \|
900:	IMRAWSDGSH \| LLPVINTTLG \| WPNGLAIDWA \| ASRLYWVDAY \| FDKIEHSTFD \|
950:	GLDRRRLGHI \| EQMTHPFGLA \| IFGEHLFFTD \| WRLGAIIRVR \| KADGGEMTVI \|
1000:	RSGIAYILHL \| KSYDVNIQTG \| SNACNQPTHP \| NGDCSHFCFP \| VPNFQRVCGC \|
1050:	PYGMRLASNH \| LTCEGDPTNE \| PPTEQCGLFS \| FPCKNGRCVP \| NYYLCDGVDD \|
1100:	CHDNSDEQLC \| GTLNNTCSSS \| AFTCGHGECI \| PAHWRCDKRN \| DCVDGSDEHN \|
1150:	CPTHAPASCL \| DTQYTCDNHQ \| CISKNWVCDT \| DNDCGDGSDE \| KNCNSTETCQ \|
1200:	PSQFNCPNHR \| CIDLSFVCDG \| DKDCVDGSDE \| VGCVLNCTAS \| QFKCASGDKC \|
1250:	IGVTNRCDGV \| FDCSDNSDEA \| GCPTRPPGMC \| HSDEFQCQED \| GICIPNFWEC \|
1300:	DGHPDCLYGS \| DEHNACVPKT \| CPSSYFHCDN \| GNCIHRAWLC \| DRDNDCGDMS \|
1350:	DEKDCPTQPF \| RCPSWQWQCL \| GHNICVNLSV \| VCDGIFDCPN \| GTDESPLCNG \|
1400:	NSCSDFNGGC \| THECVQEPFG \| AKCLCPLGFL \| LANDSKTCED \| IDECDILGSC \|
1450:	SQHCYNMRGS \| FRCSCDTGYM \| LESDGRTCKV \| TASESLLLLV \| ASQNKIIADS \|
1500:	VTSQVHNIYS \| LVENGSYIVA \| VDFDSISGRI \| FWSDATQGKT \| WSAFQNGTDR \|
1550:	RVVFDSSIIL \| TETIAIDWVG \| RNLYWTDYAL \| ETIEVSKIDG \| SHRTVLISKN \|
1600:	LTNPRGLALD \| PRMNEHLLFW \| SDWGHHPRIE \| RASMDGSMRT \| VIVQDKIFWP \|
1650:	CGLTIDYPNR \| LLYFMDSYLD \| YMDFCDYNGH \| HRRQVIASDL \| IIRHPYALTL \|
1700:	FEDSVYWTDR \| ATRRVMRANK \| WHGGNQSVVM \| YNIQWPLGIV \| AVHPSKQPNS \|
1750:	VNPCAFSRCS \| HLCLLSSQGP \| HFYSCVCPSG \| WSLSPDLLNC \| LRDDQPFLIT \|
1800:	VRQHIIFGIS \| LNPEVKSNDA \| MVPIAGIQNG \| LDVEFDDAEQ \| YIYWVENPGE \|
1850:	IHRVKTDGTN \| RTVFASISMV \| GPSMNLALDW \| ISRNLYSTNP \| RTQSIEVLTL \|
1900:	HGDIRYRKTL \| IANDGTALGV \| GFPIGITVDP \| ARGKLYWSDQ \| GTDSGVPAKI \|
1950:	ASANMDGTSV \| KTLFTGNLEH \| LECVTLDIEE \| QKLYWAVTGR \| GVIERGNVDG \|
2000:	TDRMILVHQL \| SHPWGIAVHD \| SFLYYTDEQY \| EVIERVDKAT \| GANKIVLRDN \|
2050:	VPNLRGLQVY \| HRRNAAESSN \| GCSNNMNACQ \| QICLPVPGGL \| FSCACATGFK \|
2100:	LNPDNRSCSP \| YNSFIVVSML \| SAIRGFSLEL \| SDHSETMVPV \| AGQGRNALHV \|
2150:	DVDVSSGFIY \| WCDFSSSVAS \| DNAIRRIKPD \| GSSLMNIVTH \| GIGENGVRGI \|
2200:	AVDWVAGNLY \| FTNAFVSETL \| IEVLRINTTY \| RRVLLKVTVD \| MPRHIVVDPK \|
2250:	NRYLFWADYG \| QRPKIERSFL \| DCTNRTVLVS \| EGIVTPRGLA \| VDRSDGYVYW \|
2300:	VDDSLDIIAR \| IRINGENSEV \| IRYGSRYPTP \| YGITVFENSI \| IWVDRNLKKI \|
2350:	FQASKEPENT \| EPPTVIRDNI \| NWLRDVTIFD \| KQVQPRSPAE \| VNNNPCLENN \|
2400:	GGCSHLCFAL \| PGLHTPKCDC \| AFGTLQSDGK \| NCAISTENFL \| IFALSNSLRS \|
2450:	LHLDPENHSP \| PFQTINVERT \| VMSLDYDSVS \| DRIYFTQNLA \| SGVGQISYAT \|
2500:	LSSGIHTPTV \| IASGIGTADG \| IAFDWITRRI \| YYSDYLNQMI \| NSMAEDGSNR \|
2550:	TVIARVPKPR \| AIVLDPCQGY \| LYWADWDTHA \| KIERATLGGN \| FRVPIVNSSL \|
2600:	VMPSGLTLDY \| EEDLLYWVDA \| SLQRIERSTL \| TGVDREVIVN \| AAVHAFGLTL \|
2650:	YGQYIYWTDL \| YTQRIYRANK \| YDGSGQIAMT \| TNLLSQPRGI \| NTVVKNQKQQ \|
2700:	CNNPCEQFNG \| GCSHICAPGP \| NGAECQCPHE \| GNWYLANNRK \| HCIVDNGERC \|
2750:	GASSFTCSNG \| RCISEEWKCD \| NDNDCGDGSD \| EMESVCALHT \| CSPTAFTCAN \|
2800:	GRCVQYSYRC \| DYYNDCGDGS \| DEAGCLFRDC \| NATTEFMCNN \| RRCIPREFIC \|
2850:	NGVDNCHDNN \| TSDEKNCPDR \| TCQSGYTKCH \| NSNICIPRVY \| LCDGDNDCGD \|
2900:	NSDENPTYCT \| THTCSSSEFQ \| CASGRCIPQH \| WYCDQETDCF \| DASDEPASCG \|
2950:	HSERTCLADE \| FKCDGGRCIP \| SEWICDGDND \| CGDMSDEDKR \| HQCQNQNCSD \|
3000:	SEFLCVNDRP \| PDRRCIPQSW \| VCDGDVDCTD \| GYDENQNCTR \| RTCSENEFTC \|
3050:	GYGLCIPKIF \| RCDRHNDCGD \| YSDERGCLYQ \| TCQQNQFTCQ \| NGRCISKTFV \|
3100:	CDEDNDCGDG \| SDELMHLCHT \| PEPTCPPHEF \| KCDNGRCIEM \| MKLCNHLDDC \|
3150:	LDNSDEKGCG \| INECHDPSIS \| GCDHNCTDTL \| TSFYCSCRPG \| YKLMSDKRTC \|
3200:	VDIDECTEMP \| FVCSQKCENV \| IGSYICKCAP \| GYLREPDGKT \| CRQNSNIEPY \|
3250:	LIFSNRYYLR \| NLTIDGYFYS \| LILEGLDNVV \| ALDFDRVEKR \| LYWIDTQRQV \|
3300:	IERMFLNKTN \| KETIINHRLP \| AAESLAVDWV \| SRKLYWLDAR \| LDGLFVSDLN \|
3350:	GGHRRMLAQH \| CVDANNTFCF \| DNPRGLALHP \| QYGYLYWADW \| GHRAYIGRVG \|
3400:	MDGTNKSVII \| STKLEWPNGI \| TIDYTNDLLY \| WADAHLGYIE \| YSDLEGHHRH \|
3450:	TVYDGALPHP \| FAITIFEDTI \| YWTDWNTRTV \| EKGNKYDGSN \| RQTLVNTTHR \|
3500:	PFDIHVYHPY \| RQPIVSNPCG \| TNNGGCSHLC \| LIKPGGKGFT \| CECPDDFRTL \|
3550:	QLSGSTYCMP \| MCSSTQFLCA \| NNEKCIPIWW \| KCDGQKDCSD \| GSDELALCPQ \|
3600:	RFCRLGQFQC \| SDGNCTSPQT \| LCNAHQNCPD \| GSDEDRLLCE