Catalog No.: | BTL5857T |
Applications: | IHC-p,ELISA |
Reactivity: | Human,Rat,Mouse |
Gene Name: | CASP3 CPP32 |
Protein Name: | Caspase-3 |
Human Gene Id: | 836 |
Human Swiss Prot No: | P42574 |
Mouse Gene Id: | 12367 |
Mouse Swiss Prot No: | P70677 |
Rat Swiss Prot No: | P55213 |
Immunogen: | Synthetic peptide from human protein at AA range: 134-205 |
Specificity: | The antibody detects endogenous Caspase-3 |
Formulation: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Source: | Rabbit |
Dilution: | IHC-p 1:50-200, ELISA 1:10000-20000 |
Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: | 1 mg/ml |
Storage Stability: | -20°C/1 year |
Other Name: | Caspase-3 (CASP-3) (EC 3.4.22.56) (Apopain) (Cysteine protease CPP32) (CPP-32) (Protein Yama) (SREBP cleavage activity 1) (SCA-1) [Cleaved into: Caspase-3 subunit p17; Caspase-3 subunit p12] |
Background: | CASP3 (caspase 3) encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apo |
Function: | regulation of cyclin-dependent protein kinase activity, DNA catabolic process, endonucleolytic, leuk |